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ANNOUNCEMENT: We are excited to announce that Version 3 of the DVD is currently being curated and is scheduled for release very soon. This update will include more variants and more genes, so please continue to check back with us.

The Molecular Otolaryngology & Renal Research Lab (MORL) Deafness Variation Database (DVD) provides a comprehensive guide to genetic variation in genes known to be associated with deafness. It includes all known genetic variants present in any gene that is included on OtoSCOPE®, the MORL’s comprehensive genetic deafness screening platform. This facilitates variant analysis.

The data in the MORL DVD are based on publicly available data and data from OtoSCOPE®. It also incorporates phenotypic information from the AudioGene machine-learning based audiometric profiling tool.

Variations are organized by gene and categorized as:

  • Pathogenic
  • Probable pathogenic
  • Possibly pathogenic
  • Predicted non-pathogenic
  • Probable non-pathogenic
  • Non-pathogenic
  • Unknown Significance

The DVD is updated regularly. If you would like to add a gene or variant to the database, please email or contact us online.

These data are freely available. When including information from the DVD in publication, please cite this URL and the date accessed. All content is copyrighted by the MORL at The University of Iowa.

To view or utilize this site, you must agree to the citation policy above.