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DVD v8.1 is now available! What's new?

The Molecular Otolaryngology & Renal Research Lab (MORL) Deafness Variation Database (DVD) provides a comprehensive guide to genetic variation in genes known to be associated with deafness. It includes all known genetic variants present in any gene that is included on OtoSCOPE®, the MORL's comprehensive genetic deafness screening platform. This facilitates variant analysis.

The data in the MORL DVD are based on publicly available data and data from OtoSCOPE®. The DVD also incorporates phenotypic information from the AudioGene machine-learning based audiometric profiling tool.

The goal of the DVD is to collate and annotate every variant in every deafness gene. Please take some time to review the sources we use for annotation as well as our variant classification criteria.

The DVD is continually curated. This version represents our most recent interpretation of these data and supersedes all previous versions of the DVD and variant calling as reported in Shearer AE et al, 2014. If you would like to add a gene or variant to the database, please contact us.

These data are freely available. Please review our citation policy when including information from the DVD in publication. All content is copyrighted by the MORL at The University of Iowa.

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